RT Journal Article
SR Electronic
A1 Cimrak, Ivan
A1 Bachrata, Katarina
A1 Bachraty, Hynek
A1 Jancigova, Iveta
A1 Tothova, Renata
A1 Busik, Martin
A1 Slavik, Martin
A1 Gusenbauer, Markus
T1 Object-In-Fluid Framework in Modeling of Blood Flow in Microfluidic Channels
JF Communications - Scientific Letters of the University of Zilina
YR 2016
VO 18
IS 11
SP 13
OP 20
DO 10.26552/com.C.2016.1A.13-20
UL https://komunikacie.uniza.sk/artkey/csl-201611-0002.php
AB We present a fully three-dimensional computational model of red blood cells and their flow in a fluid. This model includes all components necessary to capture important physical and biological aspects of the cell flow. It comprises descriptions of elasticity of the cell membrane, cell-cell interactions, two-way cell-fluid interaction, and adhesion of cell to surfaces.
Using this model, we analyze different processes involving flow of cells. We present the results of ongoing research concerning the development of model for cell adhesion, the analysis of microfluidic devices with periodic obstacle arrays, the optimization of microfluidic connectors and biological process of red blood cells formation from reticulocytes.